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Dr. Isha Polavarapu

Immunohematology and Blood Transfusion

Experience

Education: 

  • MD(Immunohematology and Blood Transfusion) Kasturba Medical College, Manipal (Manipal Academy of Higher Education) 2021

Skills/ Expertise:

  • Blood donor screening/phlebotomy/reaction management.
  • Apheresis (Amicus, Fresenius ComTec, Terumo Penpol Spectra Optia) – Plateletpheresis, Leukocytapheresis, Thrombocytapheresis, Granulocyte collection.
  • Peripheral blood stem cell Collection and Therapy, Bone marrow transplantation.
  • Therapeutic Plasma Exchange, Cascade double filtration plasma exchange, Immunoadsorption plasma exchange.
  • Therapeutic Platelet Rich Fibrin (PRF) & Platelet Rich Plasma preparation for surgical cases.
  • Component preparation & modifications (Leucodepletion/Irradiation/Washing /Cryopreservation of PBSC)
  • Preparation of Components for Exchange transfusion and Intra-uterine transfusion.
  • Transfusion Transmitted Infection (TTI) testing by serology (ELISA, ECi, TPHA, RPR) & molecular techniques (NAT)
  • Complete Coagulation Work-up and Interpretation.
  • Extensive Auto-Immune Hemolytic Anemia (AIHA) work-up
  • Differential adsorption and elution: Immunohematological work-up
  • Feto-maternal Hemorrhage work-up
  • Interpretation of Thromboelastography (TEG)
  • Bone marrow aspiration and biopsy

Past Experience:

  • Junior Resident Kasturba Medical College (Manipal Academy of Higher Education) June 2018.
  • Resident Doctor GROWEL Processors Pvt. Ltd, Chevuru, Andhra Pradesh June 2016 – Aug 2017–Medical Officer Saraswathi Nursing Home, Chirala, Andhra Pradesh Jan 2015 – April 2016.

Membership:

  • ISTM (Indian Society of Transfusion Medicine).

Award and Recognition:

  • ‘Post-graduate Student of The Year’ award by ISTM (Indian Society of Transfusion Medicine) at TRANSMEDCON National Conference for the year 2019.
  • First prize in Research Poster and Oral presentation on “Prevalence of Red Cell Alloimmunisation Among Transfusion Dependent Thalassemia Patients in a Tertiary Care Transfusion Centre” at 68th Indo-German Convention of Lindau Alumni Conference, Manipal, September 2018.
  • Industrial grant obtained for a project on ‘Defining and Identifying Rare Blood donors in Udupi district of Southern Karnataka’ from Bio-Rad Laboratories.
  • Seed money grant from MAHE, Manipal awarded for ‘Molecular characterization of Variant D phenotypes Among Blood Donors in Coastal Karnataka’.

Publications:

  • Isha Polavarapu, Garima Mishra, Shamee Shastry, Swati Kulkarni, “Molecular characterization of RhD variant phenotypes among blood donors: A study from the coastal region of India”, Transfusion and Apheresis Science, April 2021,103142.
  • Isha Polavarapu, Shamee Shastry. The prevalence of Dia, Mia and Mur antigens among Malaysians and Indians. Asian Journal of Transfusion Science (accepted for publication).
  • Isha Polavarapu, Shamee Shastry, Deepika Chenna. Implementation of a regional rare donor registry: An experience from South India – in Medical Journal Armed Forces of India.
  • Deepika Chenna, Isha Polavarapu, Shamee Shastry. The role of thrombocytapheresis in management of extreme thrombocytosis – A 6-year experience from a tertiary care center. Under Peer Review in Malaysian Journal of Medical Sciences.
  • Isha Polavarapu, Shamee Shastry, Akila Vasudeva. Dual Red Cell Antibody Causing Fetal Anemia: A case of variant presentation of Hemolytic Disease of Fetus. Under review in Asian Journal of Transfusion Science.

Research Presentation:

  • Presented an Oral paper on ‘Molecular Characterization of Rh D Variants Among Blood Donors from Udupi District of Coastal Karnataka’ at TRANSMEDCON 2019 National Conference conducted by Indian Society of Transfusion Medicine (ISTM) in Mumbai, January 2020.
  • Poster presentation on “Establishing a regional rare donor registry: An experience from South India” at 36th International ISBT 2020 Virtual Congress December 2020.
  • Oral presentation – “Dual Red cell antibody causing fetal anemia: A case of variant presentation of Hemolytic disease of fetus” at Advanced Immunohematology- Hands-on wet workshop at KMC, Manipal, February 2020.
  • Oral Presentation on “Prevalence of Red Cell Alloimmunisation Among Transfusion Dependent Thalassemia Patients In A Tertiary Care Transfusion Centre” at 68th Indo-German Convention of Lindau Alumni Conference, Manipal, September 2018.